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Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50009255
TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50442881(SILYBIN A)
Affinity DataKi:  700nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50442881(SILYBIN A)
Affinity DataKi:  700nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526629(ISOSILYBIN A)
Affinity DataKi:  1.10E+3nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526629(ISOSILYBIN A)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526625(CHEMBL4592595)
Affinity DataKi:  1.70E+3nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50061554((+)-Silychristin | (2R,3R)-3,5,7-Trihydroxy-2-[(2R...)
Affinity DataKi:  2.10E+3nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50061554((+)-Silychristin | (2R,3R)-3,5,7-Trihydroxy-2-[(2R...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526625(CHEMBL4592595)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataKi:  2.80E+3nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526628(ISOSILYBIN B)
Affinity DataKi:  4.20E+3nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526628(ISOSILYBIN B)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526626(CHEMBL4076992)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526626(CHEMBL4076992)
Affinity DataKi:  4.70E+3nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50442881(SILYBIN A)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50442881(SILYBIN A)
Affinity DataKi:  8.50E+3nMAssay Description:Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50084980((+)-taxifolin | (-)-Epicatechol | (2R,3R)-(-)-Epic...)
Affinity DataKi:  8.50E+3nMAssay Description:Competitive type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526628(ISOSILYBIN B)
Affinity DataKi:  1.16E+4nMAssay Description:Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526629(ISOSILYBIN A)
Affinity DataKi:  1.23E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526629(ISOSILYBIN A)
Affinity DataKi:  1.24E+4nMAssay Description:Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526628(ISOSILYBIN B)
Affinity DataKi:  1.27E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526625(CHEMBL4592595)
Affinity DataKi:  1.49E+4nMAssay Description:Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526625(CHEMBL4592595)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50061554((+)-Silychristin | (2R,3R)-3,5,7-Trihydroxy-2-[(2R...)
Affinity DataKi:  1.52E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50061554((+)-Silychristin | (2R,3R)-3,5,7-Trihydroxy-2-[(2R...)
Affinity DataKi:  1.54E+4nMAssay Description:Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526630(CHEMBL9353)
Affinity DataKi:  2.05E+4nMAssay Description:Competitive type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50084980((+)-taxifolin | (-)-Epicatechol | (2R,3R)-(-)-Epic...)
Affinity DataKi:  3.45E+4nMAssay Description:Competitive type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataKi:  3.47E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataKi:  3.55E+4nMAssay Description:Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526626(CHEMBL4076992)
Affinity DataKi:  3.67E+4nMAssay Description:Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526626(CHEMBL4076992)
Affinity DataKi:  3.83E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50240348((+)-dihydrokaempferol | (2R,3R)-3,5,7-trihydroxy-2...)
Affinity DataKi:  4.20E+4nMAssay Description:Competitive type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526630(CHEMBL9353)
Affinity DataKi:  7.34E+4nMAssay Description:Competitive type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50442881(SILYBIN A)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526629(ISOSILYBIN A)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526625(CHEMBL4592595)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50061554((+)-Silychristin | (2R,3R)-3,5,7-Trihydroxy-2-[(2R...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526627((-)-Silychristin | CHEMBL589325)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526628(ISOSILYBIN B)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526626(CHEMBL4076992)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50442881(SILYBIN A)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526625(CHEMBL4592595)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526629(ISOSILYBIN A)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526628(ISOSILYBIN B)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50084980((+)-taxifolin | (-)-Epicatechol | (2R,3R)-(-)-Epic...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50084980((+)-taxifolin | (-)-Epicatechol | (2R,3R)-(-)-Epic...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50061554((+)-Silychristin | (2R,3R)-3,5,7-Trihydroxy-2-[(2R...)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50526626(CHEMBL4076992)
Affinity DataIC50:  3.59E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  3.71E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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