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Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50008949
TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)
Affinity DataIC50:  80nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain2 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50103503(CHEMBL2393130 | US11117865, Compound RVX-208)
Affinity DataIC50:  100nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain2 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)
Affinity DataIC50:  170nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523902(CHEMBL4558228)
Affinity DataIC50:  560nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523899(CHEMBL4449543)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523901(CHEMBL4459678)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523905(CHEMBL4466270)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50103503(CHEMBL2393130 | US11117865, Compound RVX-208)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523906(CHEMBL4436750)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523900(CHEMBL4563590)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523898(CHEMBL4451445)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523907(CHEMBL4471247)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523904(CHEMBL4454528)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523908(CHEMBL4559057)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50523903(CHEMBL4456933)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of biotinylated H4 K5,8,12,16Ac peptide binding to GST-tagged BRD4 bromodomain1 (unknown origin) measured after 60 mins by AlphaScreen ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed