Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50008988
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524277(CHEMBL4451741)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524278(CHEMBL4449204)
Affinity DataIC50: 8nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524273(CHEMBL4447840)
Affinity DataIC50: 36nMAssay Description:Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524274(CHEMBL4532449)
Affinity DataIC50: 112nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50099954(CHEMBL3319605)
Affinity DataIC50: 140nMAssay Description:Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524277(CHEMBL4451741)
Affinity DataIC50: 744nMAssay Description:Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524275(CHEMBL4529201)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524276(CHEMBL4444547)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524279(CHEMBL4538766)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524273(CHEMBL4447840)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50099954(CHEMBL3319605)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed