Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50009408
Target72 kDa type IV collagenase(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528546BDBM50528546(CHEMBL4516243)
Affinity DataIC50: 620nMAssay Description:Inhibition of MMP2 catalytic domain (unknown origin) using Ac-PLG-[2-mercapto-4-methylpentanoyl]-LG-OC2H5 as substrate preincubated for 45 to 120 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 840nMAssay Description:Inhibition of COX2 (unknown origin) by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528543BDBM50528543(CHEMBL4540611)
Affinity DataIC50: 880nMAssay Description:Inhibition of COX2 (unknown origin) by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528545BDBM50528545(CHEMBL4526588)
Affinity DataIC50: 980nMAssay Description:Inhibition of recombinant human LAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProbable maltase-glucoamylase 2(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502004BDBM50502004(CHEMBL4453256)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl alpha-d-glucopyranoside as substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 152734BDBM152734(11-bromo-5-[4-(2-fluorophenyl)piperazine-1- carbon...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528544BDBM50528544(CHEMBL4587922)
Affinity DataEC50:  5.90E+3nMAssay Description:Inhibition of PPARgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProbable maltase-glucoamylase 2(Human)
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23406BDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50: 8.17E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl alpha-d-glucopyranoside as substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed