Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50009473
TargetKinesin-like protein KIF11(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50529196(CHEMBL1213953)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human His-tagged Eg5 (1 to 368 residues) assessed as reduction in ATPase activity by Bradford reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50216514(4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-1,2,3,4,...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human His-tagged Eg5 (1 to 368 residues) assessed as reduction in ATPase activity by Bradford reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50216502(monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human His-tagged Eg5 (1 to 368 residues) assessed as reduction in ATPase activity by Bradford reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed