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Found 27 Enz. Inhib. hit(s) with all data for entry = 50010714
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50148781(CHEMBL3770903)
Affinity DataIC50:  600nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50:  2.21E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H4K8Ac (3 to 13 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541418(CHEMBL4640752)
Affinity DataIC50:  4.03E+4nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541415(CHEMBL4638076)
Affinity DataIC50:  4.27E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541417(CHEMBL4634985)
Affinity DataIC50:  5.19E+4nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541414(CHEMBL4634872)
Affinity DataIC50:  5.66E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541418(CHEMBL4640752)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50:  7.36E+4nMAssay Description:Inhibition of SIRT2 defatty-acylation activity (unknown origin) using H4K8-Myr (3 to 13 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541417(CHEMBL4634985)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541418(CHEMBL4640752)
Affinity DataIC50:  7.71E+4nMAssay Description:Inhibition of SIRT2 deacetylation activity (unknown origin) using H3K9Ac ( 4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50:  8.10E+4nMAssay Description:Inhibition of SIRT2 debenzoylation activity (unknown origin) using benzoylated histone H4K8 peptide (3 to 13 residues ) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541417(CHEMBL4634985)
Affinity DataIC50:  8.49E+4nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541418(CHEMBL4640752)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541417(CHEMBL4634985)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541415(CHEMBL4638076)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541414(CHEMBL4634872)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50148781(CHEMBL3770903)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT5 desuccinylation activity (unknown origin) using H3K9Su (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541415(CHEMBL4638076)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541414(CHEMBL4634872)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50148781(CHEMBL3770903)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT3 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541416(CHEMBL4643733)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541415(CHEMBL4638076)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50148781(CHEMBL3770903)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Engineering Research Center For The Development And Application Of Ethnic Medicine And Tcm (Ministry Of Education)

Curated by ChEMBL
LigandPNGBDBM50541414(CHEMBL4634872)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SIRT1 deacetylation activity (unknown origin) using H3K9Ac (4 to 15 residues) as substrate by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed