Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50014411
LigandChemical structure of BindingDB Monomer ID 20488BDBM20488((2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse TRPM1 expressed in HEK293T cells assessed as blocked of capsaicin-activated current at 10 uM by whole cell patch clamp electrophy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50575835BDBM50575835(CHEMBL4878260)
Affinity DataIC50: 13nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242184BDBM50242184(Scalaradial)
Affinity DataIC50: 210nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50575838BDBM50575838(CHEMBL4863360)
Affinity DataIC50: 398nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50575841BDBM50575841(CHEMBL4864346)
Affinity DataIC50: 410nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50575839BDBM50575839(CHEMBL4856222)
Affinity DataIC50: 467nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50575837BDBM50575837(CHEMBL4863549)
Affinity DataIC50: 788nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50575836BDBM50575836(CHEMBL4849043)
Affinity DataIC50: 830nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50575840BDBM50575840(CHEMBL4856093)
Affinity DataIC50: 987nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50278349BDBM50278349(2-(Diphenylboryloxy)Ethanamine | 2-Aminoethoxydiph...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50227083BDBM50227083(CHEMBL173443)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50291511BDBM50291511(2-((E)-3-Biphenyl-4-yl-acryloylamino)-benzoic acid...)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 31773BDBM31773(ECONAZOLE | cid_68589 | Pevaryl | Gyno-pevaryl | E...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 31774BDBM31774(cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50405913BDBM50405913(CHEMBL4176916)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50227083BDBM50227083(CHEMBL173443)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human TRPM8 expressed in HEK293T cells assessed as blocked of menthol-activated current by whole cell patch clamp electrophysiology rel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20488BDBM20488((2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRPM8 expressed in HEK293T cells assessed as blocked of menthol-activated current by whole cell patch clamp electrophysiology rel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50227083BDBM50227083(CHEMBL173443)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PLA2 (unknown origin) using soybean phosphatidylcholine as substrate preincubated for 30 mins followed incubated for 60 mins after subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17636BDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50385713BDBM50385713(CHEMBL23479)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed