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Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50018255 Sort by
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50408824(CHAULMOOGRIC ACID | CHEBI:61391 | Chaulmoogric Aci...)
Affinity DataEC50:  1.30nMAssay Description:Activation of recombinant human PP5 (16 to 499 residues) Escherichia coli BL21 (DE3) using pNPP incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM22319([1-14C]Arachidonic acid | (5Z,8Z,11Z,14Z)-icosa-5,...)
Affinity DataEC50:  7.80nMAssay Description:Activation of recombinant human PP5 (16 to 499 residues) Escherichia coli BL21 (DE3) using pNPP incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(Bovine)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110681(Calyculin-A | CHEMBL430266)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human PP2AC using [3H]-phosphohistone as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 6 catalytic subunit(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50408820(CHEMBL5268133)
Affinity DataIC50: 1nMAssay Description:Inhibition of PP6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PP5 (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061067(8-[3-amino(imino)methylaminopropyl]-15-isobutyl-5-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110681(Calyculin-A | CHEMBL430266)
Affinity DataIC50: 3nMAssay Description:Inhibition of human PP5 using [3H]-phosphohistone as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50408820(CHEMBL5268133)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50408822(CHEMBL5276260)
Affinity DataIC50: 4nMAssay Description:Inhibition of PP5 (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 6 catalytic subunit(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50090505((1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PP6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50366883(TAUTOMYCIN)
Affinity DataIC50: 10nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 6 catalytic subunit(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110681(Calyculin-A | CHEMBL430266)
Affinity DataIC50: 10nMAssay Description:Inhibition of PP6 (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50408823(CHEMBL5276593)
Affinity DataIC50: 12nMAssay Description:Inhibition of PP5 (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(Bovine)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50090505((1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 160nMAssay Description:Inhibition of PP2A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(Bovine)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50408821(CHEMBL5270968)
Affinity DataIC50: 400nMAssay Description:Inhibition of human PP2AC using [3H]-phosphohistone as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50090505((1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human PP5 using [3H]-phosphohistone as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50090505((1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 600nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed