Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50014897
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35905BDBM35905(cid_610479 | flufenamic acid analogue, 32 | Tolfen...)
Affinity DataIC50: 880nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580867BDBM50580867(CHEMBL5093769)
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008935BDBM50008935(CHEMBL84 | 10-Dimethylaminomethyl-4-ethyl-4,9-dihy...)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580870BDBM50580870(CHEMBL5087462)
Affinity DataIC50: 3.36E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580870BDBM50580870(CHEMBL5087462)
Affinity DataIC50: 3.36E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580880BDBM50580880(CHEMBL5092199)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580880BDBM50580880(CHEMBL5092199)
Affinity DataIC50: 4.76E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580877BDBM50580877(CHEMBL5094564)
Affinity DataIC50: 4.81E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580879BDBM50580879(CHEMBL5087242)
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580873BDBM50580873(CHEMBL5081898)
Affinity DataIC50: 6.12E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580881BDBM50580881(CHEMBL5089985)
Affinity DataIC50: 7.09E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580877BDBM50580877(CHEMBL5094564)
Affinity DataIC50: 8.56E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580874BDBM50580874(CHEMBL5074784)
Affinity DataIC50: 8.57E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580878BDBM50580878(CHEMBL5080484)
Affinity DataIC50: 9.26E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580884BDBM50580884(CHEMBL5090197)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580884BDBM50580884(CHEMBL5090197)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580868BDBM50580868(CHEMBL5085349)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580875BDBM50580875(CHEMBL5088859)
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580881BDBM50580881(CHEMBL5089985)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580879BDBM50580879(CHEMBL5087242)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580882BDBM50580882(CHEMBL5079590)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580866BDBM50580866(CHEMBL5078677)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580883BDBM50580883(CHEMBL5094553)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580867BDBM50580867(CHEMBL5093769)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580885BDBM50580885(CHEMBL5090568)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580869BDBM50580869(CHEMBL5078291)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404946BDBM50404946(CHEMBL4172542)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580871BDBM50580871(CHEMBL5082822)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580872BDBM50580872(CHEMBL5076562)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580876BDBM50580876(CHEMBL5094539)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580878BDBM50580878(CHEMBL5080484)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404946BDBM50404946(CHEMBL4172542)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580866BDBM50580866(CHEMBL5078677)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580868BDBM50580868(CHEMBL5085349)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580869BDBM50580869(CHEMBL5078291)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580871BDBM50580871(CHEMBL5082822)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580872BDBM50580872(CHEMBL5076562)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580873BDBM50580873(CHEMBL5081898)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580874BDBM50580874(CHEMBL5074784)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580875BDBM50580875(CHEMBL5088859)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580876BDBM50580876(CHEMBL5094539)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580882BDBM50580882(CHEMBL5079590)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580883BDBM50580883(CHEMBL5094553)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580885BDBM50580885(CHEMBL5090568)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed