Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50014635
TargetHigh affinity nerve growth factor receptor(Human)
Veterinary Medicine Research & Development
Curated by ChEMBL
Veterinary Medicine Research & Development
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation pretreated for 20 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Veterinary Medicine Research & Development
Curated by ChEMBL
Veterinary Medicine Research & Development
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human TRKA expressed in human U2OS cells assessed as inhibition of substrate hydrolysis pretreated for 30 mins followed by NGF agonist ...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Veterinary Medicine Research & Development
Curated by ChEMBL
Veterinary Medicine Research & Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation using CSKtide as a substrate pretreated for 20 mins fo...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Veterinary Medicine Research & Development
Curated by ChEMBL
Veterinary Medicine Research & Development
Curated by ChEMBL
Affinity DataEC50: 61nMAssay Description:Binding affinity to human full length TRKA at inactive state expressed in rat PC-12 cells assessed as induction of kinase conformational change at 40...More data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Human)
Veterinary Medicine Research & Development
Curated by ChEMBL
Veterinary Medicine Research & Development
Curated by ChEMBL
Affinity DataIC50: 289nMAssay Description:Inhibition of human TRKB expressed in human U2OS cells assessed as inhibition of substrate hydrolysis pretreated for 30 mins followed by BDNF agonist...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Veterinary Medicine Research & Development
Curated by ChEMBL
Veterinary Medicine Research & Development
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to human full length TRKA at active state expressed in rat PC-12 cells assessed as induction of kinase conformational change at 52 d...More data for this Ligand-Target Pair
