Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50014969
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581608(CHEMBL5082760)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227513(2-(thiophen-2-yl)ethanamine | CHEMBL252803)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581616(CHEMBL4555465)
Affinity DataEC50:  25nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581604(ULOTARONT | Ulotaront | Sep-363856 | SEP-363856 | ...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581606(CHEMBL5094122)
Affinity DataEC50:  51nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581613(CHEMBL5077361)
Affinity DataEC50:  65nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM29135(CHEMBL11608 | cid_5610 | tyramine | p-Tyramine)
Affinity DataEC50:  76nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581615(CHEMBL5093297)
Affinity DataEC50:  113nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240500(N-methyl-2-phenylelthylamine | Methyl-phenethyl-am...)
Affinity DataEC50:  151nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581609(CHEMBL5094071)
Affinity DataEC50:  203nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359505(CHEMBL1182312)
Affinity DataEC50:  225nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581611(CHEMBL5079591)
Affinity DataEC50:  233nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581614(CHEMBL5083638)
Affinity DataEC50:  290nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataEC50:  308nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581612(CHEMBL5076544)
Affinity DataEC50:  321nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50020502(2-(3-hydroxyphenyl)ethylamine | 2-(3-Hydroxy-pheny...)
Affinity DataEC50:  339nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581605(CHEMBL5080235)
Affinity DataEC50:  645nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581602(CHEMBL1160703 | CHEBI:44715)
Affinity DataEC50:  1.57E+3nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  1.71E+3nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
Affinity DataEC50:  2.21E+3nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581603(CHEMBL1235033 | CHEBI:44808)
Affinity DataEC50:  4.11E+3nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292375(Synephrine,(+/-) | (-)-Synephrine | D-synephrine |...)
Affinity DataEC50:  4.73E+3nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581610(CHEMBL5088853)
Affinity DataEC50:  7.20E+3nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM35234(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
Affinity DataEC50:  1.22E+4nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  3.51E+4nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50581607(CHEMBL5094291)
Affinity DataEC50:  4.57E+4nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed