Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50016683
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 710nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596547(CHEMBL5193426)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596546(CHEMBL5194241)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596548(CHEMBL5205284)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596549(CHEMBL5175965)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596544(CHEMBL5204503)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596550(CHEMBL5171374)
Affinity DataIC50: 4.49E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596551(CHEMBL5171189)
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp measured after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50596545(CHEMBL5170888)
Affinity DataIC50: 7.58E+3nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp in presence of doxorubicin measured after 52 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of P-gp mediated doxorubicin resistance in human SW620/AD300 cells overexpressing P-gp measured after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed