Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50015341
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to kinase tracer 236 binding to His tagged recombinant human CDK8/cyclinC assessed as dissociation constant by TR FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50248629(CHEMBL4076837 | US11471446, Compound DBA-9)
Affinity DataKd:  2nMAssay Description:Binding affinity to kinase tracer 236 binding to His tagged recombinant human CDK8/cyclinC assessed as dissociation constant by TR FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to recombinant human CDK19/cyclinC assessed as dissociation constant by TR FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50248629(CHEMBL4076837 | US11471446, Compound DBA-9)
Affinity DataKd:  3nMAssay Description:Binding affinity to recombinant human CDK19/cyclinC assessed as dissociation constant by TR FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585705(CHEMBL4856755 | US12281080, SCCP 6219)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585702(CHEMBL4868007)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585701(CHEMBL5080406 | US12281080, SCCP 6299)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585700(CHEMBL5087015)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585696(CHEMBL4851694 | US12281080, SCCP 6283)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585703(CHEMBL5094174 | US12281080, SCCP 6346)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585704(CHEMBL5077066 | US12281080, SCCP 6345)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585699(CHEMBL5094334 | US12281080, SCCP 6294)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585706(CHEMBL5087807 | US12281080, SCCP 6337)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585707(CHEMBL5091221 | US12281080, SCCP 6336)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50248629(CHEMBL4076837 | US11471446, Compound DBA-9)
Affinity DataIC50: 11nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585697(CHEMBL5086592 | US12281080, SCCP 6326)
Affinity DataIC50: 12nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585684(CHEMBL4855789)
Affinity DataIC50: 17nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585698(CHEMBL5083266 | US12281080, SCCP 6440)
Affinity DataIC50: 19nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585690(CHEMBL4863646)
Affinity DataIC50: 20nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50459994(CHEMBL4226806 | US11471446, Compound DBA-8)
Affinity DataIC50: 35nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585686(CHEMBL4871564)
Affinity DataIC50: 44nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-dependent kinase 19(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataKd:  44nMAssay Description:Binding affinity to human CDK19 assessed as dissociation constant by KdELECT Discover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataKd:  55nMAssay Description:Binding affinity to human CDK8 assessed as dissociation constant by KdELECT Discover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585687(CHEMBL4857902)
Affinity DataIC50: 183nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585688(CHEMBL5078784)
Affinity DataIC50: 212nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585689(CHEMBL5081291)
Affinity DataIC50: 356nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataKd:  940nMAssay Description:Binding affinity to human MAP4K2 assessed as dissociation constant by KdELECT Discover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585685(CHEMBL5080239)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585692(CHEMBL4857688)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585691(CHEMBL5088692)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human HASPIN assessed as dissociation constant by KdELECT Discover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585693(CHEMBL5093671)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCyclin-C(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585695(CHEMBL4875076)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMyosin-IIIb(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to human MYO3B assessed as dissociation constant by KdELECT Discover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed