Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50017638
TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50603567(CHEMBL5172755)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at CXCR4 receptor in SDF-1alpha-stimulated human SUP-T1 cells measured by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at CXCR4 receptor in SDF-1alpha-stimulated human SUP-T1 cells measured by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50603567(CHEMBL5172755)
Affinity DataIC50: 12nMAssay Description:Binding affinity to CXCR4 (unknown origin) expressed in CHO cells measured by 12G5 competitive binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50603568(CHEMBL5197361)
Affinity DataKd:  33nMAssay Description:Binding affinity to CXCR4 (unknown origin) expressed in CHO cells measured by Scatchard plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50603567(CHEMBL5172755)
Affinity DataIC50: 236nMAssay Description:Antagonist activity at CXCR4 receptor in human SUP-T1 cells assessed as reduction in SDF-1alpha-stimulated cell migration and measured by CellTiter-9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 320nMAssay Description:Binding affinity to CXCR4 (unknown origin) expressed in CHO cells measured by 12G5 competitive binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 625nMAssay Description:Antagonist activity at CXCR4 receptor in human SUP-T1 cells assessed as reduction in SDF-1alpha-stimulated cell migration and measured by CellTiter-9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)