Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50017899
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605941(CHEMBL5200001)
Affinity DataEC50:  103nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605928(CHEMBL5195160)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605955(CHEMBL5177145)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605954(CHEMBL5194692)
Affinity DataEC50:  69nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605953(CHEMBL5191110)
Affinity DataEC50:  206nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605952(CHEMBL5185447)
Affinity DataEC50:  55nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605951(CHEMBL5205161)
Affinity DataEC50:  860nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605950(CHEMBL5179980)
Affinity DataEC50:  366nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605949(CHEMBL5173653)
Affinity DataEC50:  407nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605948(CHEMBL5169615)
Affinity DataEC50:  915nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605947(CHEMBL5202767)
Affinity DataEC50:  54nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605946(CHEMBL5190176)
Affinity DataEC50:  435nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605945(CHEMBL5171656)
Affinity DataEC50:  98nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605944(CHEMBL5208855)
Affinity DataEC50:  173nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605943(CHEMBL5205025)
Affinity DataEC50:  217nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605942(CHEMBL5178316)
Affinity DataEC50:  369nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605940(CHEMBL5203677)
Affinity DataEC50:  285nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605927(CHEMBL5172913)
Affinity DataEC50:  14nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605939(CHEMBL5177134)
Affinity DataEC50:  1.40E+3nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605938(CHEMBL5192837)
Affinity DataEC50:  1.04E+3nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605937(CHEMBL5209542)
Affinity DataEC50:  1.42E+4nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605936(CHEMBL5193017)
Affinity DataEC50:  9.01E+3nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605935(CHEMBL5181857)
Affinity DataEC50:  1.09E+3nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605934(CHEMBL5176049)
Affinity DataEC50:  1.36E+3nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605933(CHEMBL5188039)
Affinity DataEC50:  502nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605932(CHEMBL5191409)
Affinity DataEC50:  506nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605931(CHEMBL5207586)
Affinity DataEC50:  3.14E+3nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605930(CHEMBL5193744)
Affinity DataEC50:  2.83E+3nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605929(CHEMBL5177388)
Affinity DataEC50:  124nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMas-related G-protein coupled receptor member X1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605956(CHEMBL5205606)
Affinity DataEC50:  31nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605928(CHEMBL5195160)
Affinity DataKi:  71nMAssay Description:Binding affinity to peripheral benzodiazepine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605927(CHEMBL5172913)
Affinity DataKi:  271nMAssay Description:Binding affinity to peripheral benzodiazepine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605954(CHEMBL5194692)
Affinity DataKi:  1.09E+3nMAssay Description:Binding affinity to H1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605927(CHEMBL5172913)
Affinity DataKi: >4.00E+3nMAssay Description:Binding affinity to D5 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50605927(CHEMBL5172913)
Affinity DataKi: >4.00E+3nMAssay Description:Binding affinity to H1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed