Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50016807
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataKd:  0.280nMAssay Description:Binding affinity to human RIPK1 in human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataKd:  0.280nMAssay Description:Binding affinity to human RIPK2 in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597341BDBM50597341(CHEMBL5187454)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597338BDBM50597338(CHEMBL5195615)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597344BDBM50597344(CHEMBL5171377)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597336BDBM50597336(CHEMBL5197634)
Affinity DataIC50: 3nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597330BDBM50597330(CHEMBL5205764)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597340BDBM50597340(CHEMBL5205532)
Affinity DataIC50: 4nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597325BDBM50597325(CHEMBL5174069)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597332BDBM50597332(CHEMBL5171074)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597342BDBM50597342(CHEMBL5169942)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597328BDBM50597328(CHEMBL5187179)
Affinity DataIC50: 6nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597337BDBM50597337(CHEMBL5184606)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597339BDBM50597339(CHEMBL5180091)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597334BDBM50597334(CHEMBL5175396)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597346BDBM50597346(CHEMBL5191232)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597343BDBM50597343(CHEMBL5207306)
Affinity DataIC50: 9nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597327BDBM50597327(CHEMBL5191796)
Affinity DataIC50: 11nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597345BDBM50597345(CHEMBL5174176)
Affinity DataIC50: 11nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597326BDBM50597326(CHEMBL5189173)
Affinity DataIC50: 12nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataIC50: 15nMAssay Description:Inhibition of human DDR1 by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597329BDBM50597329(CHEMBL5172982)
Affinity DataIC50: 16nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597331BDBM50597331(CHEMBL5204246)
Affinity DataIC50: 17nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597335BDBM50597335(CHEMBL5170201)
Affinity DataIC50: 19nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597333BDBM50597333(CHEMBL5185309)
Affinity DataIC50: 21nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597347BDBM50597347(CHEMBL5206121)
Affinity DataIC50: 34nMAssay Description:Inhibition of human RIPK2 incubated for 120 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataIC50: 56nMAssay Description:Inhibition of human c-SRC by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataKd:  75nMAssay Description:Binding affinity to human RIPK3 in human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataIC50: 89nMAssay Description:Inhibition of human SIK by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDual serine/threonine and tyrosine protein kinase(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataKd:  670nMAssay Description:Binding affinity to human RIPK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataIC50: 862nMAssay Description:Inhibition of human PDGFRbeta by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human KIT by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 4(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to human RIPK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibition of human FLT3 by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597348BDBM50597348(CHEMBL5177284)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human RIPK1 by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed