Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50016359
TargetDiacylglycerol O-acyltransferase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530621(WO2022076495, EXAMPLE 65 | 1-(5-(difluoromethoxy)-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50594461(CHEMBL5202996)
Affinity DataIC50: 1nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50594459(CHEMBL5179522)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50594462(CHEMBL5194578)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50594460(CHEMBL5188169)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530556(WO2022076495, EXAMPLE 2 | 1-(3-(difluoromethoxy)ph...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed