TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 0.708nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: <50nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: <50nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: <50nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of 20S proteasome beta2 subunit (unknown origin) using Boc-LRR-AMC as flurogenic substrate measured after 1 hr by fluorescence based analy...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibition of 20S proteasome beta1 subunit (unknown origin) using Z-LLE-AMC as flurogenic substrate measured after 1 hr by fluorescence based analysi...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 141nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 151nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair