BDBM50593010 CHEMBL5198758

SMILES CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)c1cc(Cl)ccc1Cl)B(O)O

InChI Key InChIKey=GXXXAPFVFBGPCW-STQMWFEESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593010   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50593010(CHEMBL5198758)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50593010(CHEMBL5198758)
Affinity DataIC50:  513nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed