TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at -120 mV holding potential by automated patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant rat Nav1.4 expressed in CHO cells by whole cell voltage clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: >100nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 702nMAssay Description:Inhibition of human Nav1.7 expressed in CHO cells at -100 mV holding potential by electrophysiology whole cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of mouse Nav1.7 at -120 mV holding potential by automated patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of recombinant human Nav1.5 expressed in CHO cells by whole cell voltage clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibition of rat Nav1.7 at -120 mV holding potential by automated patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 6.53E+4nMAssay Description:Inhibition of human Nav1.3 expressed in CHO cells at -120 mV holding potential by automated patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair