Compile Data Set for Download or QSAR
Report error Found 191 Enz. Inhib. hit(s) with all data for entry = 50019508
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619956(CHEMBL5418170)
Affinity DataEC50:  30nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in IL-6 level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619956(CHEMBL5418170)
Affinity DataEC50:  120nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in CXCL10 level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619956(CHEMBL5418170)
Affinity DataEC50:  270nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in IFN-beta level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619973(CHEMBL5404076)
Affinity DataEC50:  530nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619935(CHEMBL5434030)
Affinity DataEC50:  930nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619972(CHEMBL5411918)
Affinity DataEC50:  1.12E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619976(CHEMBL5422843)
Affinity DataEC50:  1.42E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619956(CHEMBL5418170)
Affinity DataEC50:  1.58E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619974(CHEMBL5406252)
Affinity DataEC50:  2.19E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619977(CHEMBL5434223)
Affinity DataEC50:  2.96E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619956(CHEMBL5418170)
Affinity DataEC50:  3.20E+3nMAssay Description:Activation of STING signalling pathway in human THP1-Dual cells assessed as increase in IRF-luciferase activation incubated for 24 hrs by QUANTI-luc ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619961(CHEMBL5416345)
Affinity DataEC50:  3.22E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619959(CHEMBL5407882)
Affinity DataEC50:  3.57E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619960(CHEMBL5438258)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619943(CHEMBL5409634)
Affinity DataEC50:  4.13E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619957(CHEMBL5401091)
Affinity DataEC50:  4.17E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619956(CHEMBL5418170)
Affinity DataEC50:  4.74E+3nMAssay Description:Activation of STING signalling pathway in human wild type THP-1 cells assessed as increase in IFN-beta secretion incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619958(CHEMBL5403859)
Affinity DataEC50:  5.14E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619964(CHEMBL5397486)
Affinity DataEC50:  5.28E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619956(CHEMBL5418170)
Affinity DataEC50:  5.50E+3nMAssay Description:Activation of STING signalling pathway in human THP1-Dual cells assessed as increase in NF-kappaB-SEAP activation incubated for 24 hrs by QUANTI-Blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619944(CHEMBL5407521)
Affinity DataEC50:  7.04E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619975(CHEMBL5428199)
Affinity DataEC50:  7.13E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619953(CHEMBL5398312)
Affinity DataEC50:  8.52E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619978(CHEMBL5405745)
Affinity DataEC50:  9.73E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619941(CHEMBL5396923)
Affinity DataEC50:  9.81E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619942(CHEMBL5403697)
Affinity DataEC50:  9.83E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619969(CHEMBL5400245)
Affinity DataEC50:  1.12E+4nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.14E+4nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.28E+4nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in CXCL10 level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619962(CHEMBL5426173)
Affinity DataEC50:  1.31E+4nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.38E+4nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells by luciferase gene reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.40E+4nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in IFN-beta level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.90E+4nMAssay Description:Activation of STING signalling pathway in human THP1-Dual cells assessed as increase in IRF-luciferase activation incubated for 24 hrs by QUANTI-luc ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  2.50E+4nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in IL-6 level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619967(CHEMBL5407052)
Affinity DataEC50:  2.88E+4nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619971(CHEMBL5404906)
Affinity DataEC50:  3.94E+4nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619966(CHEMBL5420486)
Affinity DataEC50:  4.09E+4nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  4.38E+4nMAssay Description:Activation of STING signalling pathway in human THP1-Dual cells assessed as increase in NF-kappaB-SEAP activation incubated for 24 hrs by QUANTI-Blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619901(CHEMBL5412376)
Affinity DataEC50:  4.71E+4nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619963(CHEMBL5407012)
Affinity DataEC50:  9.63E+4nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619947(CHEMBL5428418)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619948(CHEMBL5420776)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619945(CHEMBL5421842)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619946(CHEMBL5393940)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619951(CHEMBL5408949)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619952(CHEMBL5430995)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619949(CHEMBL5417145)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619950(CHEMBL5394912)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619955(CHEMBL5425690)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50619956(CHEMBL5418170)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
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