Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50018201
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336799BDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataIC50: 260nMAssay Description:Inhibition of SARS-CoV-2 RdRp expressed in Escherichia coli BL21 (DE3) cells incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406113BDBM50406113(CHEMBL5279597)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406116BDBM50406116(CHEMBL5286682)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406069BDBM50406069(CHEMBL5278945)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406062BDBM50406062(CHEMBL5280903)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7459BDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406065BDBM50406065(CHEMBL3326854)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406067BDBM50406067(CHEMBL5272459)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406110BDBM50406110(CHEMBL5284676)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406064BDBM50406064(CHEMBL594248)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406066BDBM50406066(CHEMBL5284680)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7460BDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406111BDBM50406111(CHEMBL228623)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406112BDBM50406112(CHEMBL5279962)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406068BDBM50406068(CHEMBL5281399)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406063BDBM50406063(CHEMBL5271510)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406115BDBM50406115(CHEMBL5279136)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525250BDBM50525250(CHEMBL4526128)
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of SARS-CoV-2 RdRp incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406114BDBM50406114(CHEMBL5281483)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406070BDBM50406070(CHEMBL5281756)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SARS-CoV-2 RdRp using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed