Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 50022249
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649885(CHEMBL5624885)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of recombinant PDE7A1 (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649871(CHEMBL5625125)
Affinity DataIC50: 0.760nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649872(Gsk-356278 | Gsk356278 | GSK356278 | GSK356278B)
Affinity DataIC50: 0.760nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50068287(CHEMBL3403346)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PDE7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649872(Gsk-356278 | Gsk356278 | GSK356278 | GSK356278B)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649877(CHEMBL5625053)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649876(CHEMBL5630856)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649881(CHEMBL5625119)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM607111(US11685745, Example 189)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant PDE7A1 (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM607104(US11685745, Example 37)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant PDE7A1 (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649870(CHEMBL5630984)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE7B (unknown origin) by 3H-cAMP scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151605(4-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant PDE7 (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PDE7 (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649871(CHEMBL5625125)
Affinity DataIC50: 19nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649880(CHEMBL5624926)
Affinity DataIC50: 20nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649869(CHEMBL5625140)
Affinity DataIC50: 23nMAssay Description:Inhibition of PDE7B (unknown origin) by 3H-cAMP scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM135584(US8846654, 294)
Affinity DataIC50: 37nMAssay Description:Inhibition of PDE7 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM135577(US8846654, 11)
Affinity DataIC50: 39nMAssay Description:Inhibition of PDE7 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM135583(US8846654, 251)
Affinity DataIC50: 46nMAssay Description:Inhibition of PDE7 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50068287(CHEMBL3403346)
Affinity DataIC50: 46nMAssay Description:Inhibition of PDE4 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151647(8''-chloro-5''-(2-hydroxyethoxy)spiro[cyclohexane-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151647(8''-chloro-5''-(2-hydroxyethoxy)spiro[cyclohexane-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant PDE7 (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151533(4-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human PDE4D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649879(CHEMBL5624721)
Affinity DataIC50: 74nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649883(CHEMBL5630835)
Affinity DataIC50: 88nMAssay Description:Inhibition of human PDE4D3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM350888(US9796687, Compound 5 | 3-Phenyl-2-neopentylthio-4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649868(CHEMBL5630424)
Affinity DataIC50: 112nMAssay Description:Inhibition of PDE4A1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649875(CHEMBL5629944)
Affinity DataIC50: 130nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649868(CHEMBL5630424)
Affinity DataIC50: 142nMAssay Description:Inhibition of recombinant PDE7A1 (130 to 482 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151547(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human PDE4D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151628(8''-chlorospiro[cyclohexane-1,4''-(1'',2'',3'',4''...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant PDE7 (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649886(CHEMBL5624639)
Affinity DataIC50: 171nMAssay Description:Inhibition of recombinant PDE7A1 (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50277784(N,N,2-trimethyl-5-nitrobenzenesulfonamide | CHEMBL...)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant PDE7A1 (130 to 482 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649868(CHEMBL5630424)
Affinity DataIC50: 305nMAssay Description:Inhibition of PDE4B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649884(CHEMBL5630169)
Affinity DataIC50: 380nMAssay Description:Inhibition of PDE7 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50356366(CHEMBL1911416)
Affinity DataIC50: 380nMAssay Description:Inhibition of PDE4 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 510nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649887(CHEMBL5630504)
Affinity DataIC50: 543nMAssay Description:Inhibition of PDE4B1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50359737(CHEMBL1927722)
Affinity DataIC50: 550nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649883(CHEMBL5630835)
Affinity DataIC50: 616nMAssay Description:Inhibition of recombinant PDE7A1 (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50277784(N,N,2-trimethyl-5-nitrobenzenesulfonamide | CHEMBL...)
Affinity DataIC50: 620nMAssay Description:Inhibition of PDE7B (unknown origin) by 3H-cAMP scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50356366(CHEMBL1911416)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant PDE7A1 (130 to 482 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50648239(CHEMBL5613951)
Affinity DataIC50: 880nMAssay Description:Inhibition of GSK3beta (unknown origin) activity assessed as fluorescence intensity by ADP-Glo Kinase AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50382627(CHEMBL2024362)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of PDE7 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649874(CHEMBL3545918)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649878(CHEMBL5630770)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of full length PDE7 (unknown origin) using FAM-cAMP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649884(CHEMBL5630169)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) activity assessed as fluorescence intensity by ADP-Glo Kinase AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50649875(CHEMBL5629944)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PDE4 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50559720(CHEMBL4756052)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant PDE7A1 (130 to 482 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human recombinant PDE4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
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