Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50018927
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350311BDBM50350311(CHEMBL1812661)
Affinity DataKd:  5nMAssay Description:Inhibition of human Arginase I in human myeloid-derived suppressor cells using L-arginine as substrate assessed as L-ornithine product formation by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008099BDBM50008099(CHEMBL1234777)
Affinity DataKd:  50nMAssay Description:Inhibition of human Arginase I assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613887BDBM50613887(CHEMBL5272577)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613887BDBM50613887(CHEMBL5272577)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613892BDBM50613892(CHEMBL5280882)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613880BDBM50613880(CHEMBL5272837)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613888BDBM50613888(CHEMBL5279229)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613888BDBM50613888(CHEMBL5279229)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613880BDBM50613880(CHEMBL5272837)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613889BDBM50613889(CHEMBL5266555)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613881BDBM50613881(CHEMBL5271123)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613878BDBM50613878(CHEMBL5278560)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613893BDBM50613893(CHEMBL5289153)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613881BDBM50613881(CHEMBL5271123)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613892BDBM50613892(CHEMBL5280882)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613878BDBM50613878(CHEMBL5278560)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613889BDBM50613889(CHEMBL5266555)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613882BDBM50613882(CHEMBL5269808)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613882BDBM50613882(CHEMBL5269808)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613890BDBM50613890(CHEMBL5284872)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613879BDBM50613879(CHEMBL5265901)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613890BDBM50613890(CHEMBL5284872)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613883BDBM50613883(CHEMBL5270828)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613883BDBM50613883(CHEMBL5270828)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613879BDBM50613879(CHEMBL5265901)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613884BDBM50613884(CHEMBL5269767)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613885BDBM50613885(CHEMBL5284426)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613885BDBM50613885(CHEMBL5284426)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613891BDBM50613891(CHEMBL5281093)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613884BDBM50613884(CHEMBL5269767)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613886BDBM50613886(CHEMBL5278843)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613886BDBM50613886(CHEMBL5278843)
Affinity DataIC50: 5.03E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613891BDBM50613891(CHEMBL5281093)
Affinity DataIC50: 9.22E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed