Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50019679
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 247411BDBM247411(US9453018, 353 | US10336754, Example 353 | US11053...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity to FXIa (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621714BDBM50621714(CHEMBL5413065)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to FXIa (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621696BDBM50621696(CHEMBL5426362)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621695BDBM50621695(CHEMBL5397593)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621705BDBM50621705(CHEMBL5399926)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621701BDBM50621701(CHEMBL5426898)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 413849BDBM413849(US10421742, Example 242 | 4-{[(2S)-2-{4-[5-Chloro-...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 304114BDBM304114((R)-2-(1-((4-carboxyphenyl)amino)-3-cyclopropyl-1-...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621705BDBM50621705(CHEMBL5399926)
Affinity DataIC50: 1nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 413842BDBM413842(US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621711BDBM50621711(CHEMBL5405738)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human FXIa by absorbance based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621698BDBM50621698(CHEMBL5426903)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621693BDBM50621693(CHEMBL5395901)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621692BDBM50621692(CHEMBL5416175)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621699BDBM50621699(CHEMBL5403224)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621712BDBM50621712(CHEMBL5416419)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FXIa by absorbance based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 303810BDBM303810(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621694BDBM50621694(CHEMBL5415591)
Affinity DataKi:  2nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 335393BDBM335393(US9732085, 57 | methyl{4-[5-chloro-2-({4-[5-chloro...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621691BDBM50621691(CHEMBL5407365)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50220841BDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human FXIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621700BDBM50621700(CHEMBL5395367)
Affinity DataIC50: 3nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50542723BDBM50542723(CHEMBL4643449)
Affinity DataIC50: 3nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50542723BDBM50542723(CHEMBL4643449)
Affinity DataIC50: 3nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621697BDBM50621697(CHEMBL5403102)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621690BDBM50621690(CHEMBL5436769)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621703BDBM50621703(CHEMBL5401018)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621715BDBM50621715(CHEMBL5416393)
Affinity DataKi:  5nMAssay Description:Binding affinity to FXIa (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTryptase delta(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50220841BDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 5nMAssay Description:Inhibition of human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 413849BDBM413849(US10421742, Example 242 | 4-{[(2S)-2-{4-[5-Chloro-...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621689BDBM50621689(CHEMBL5410680)
Affinity DataKi:  6nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50542735BDBM50542735(CHEMBL4635286)
Affinity DataIC50: 6nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621704BDBM50621704(CHEMBL5411143)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320260BDBM320260(US10174020, Compound 8-1)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 413842BDBM413842(US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586027BDBM50586027(CHEMBL5090877)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621716BDBM50621716(FRUNEXIAN | Frunexian | EP-7041)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human FXIaMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621702BDBM50621702(CHEMBL5408222)
Affinity DataIC50: 10nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621706BDBM50621706(CHEMBL5437123)
Affinity DataIC50: 10nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 607616BDBM607616(US11691962, Compound 1-13)
Affinity DataIC50: 10nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621699BDBM50621699(CHEMBL5403224)
Affinity DataIC50: 13nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 335392BDBM335392(US9732085, 45 | US10717738, Example 45)
Affinity DataIC50: 15nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 304114BDBM304114((R)-2-(1-((4-carboxyphenyl)amino)-3-cyclopropyl-1-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetComplement factor D(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50542723BDBM50542723(CHEMBL4643449)
Affinity DataIC50: 40nMAssay Description:Inhibition of FD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621701BDBM50621701(CHEMBL5426898)
Affinity DataIC50: 42nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621713BDBM50621713(CHEMBL5410718)
Affinity DataIC50: 43nMAssay Description:Inhibition of human FXIa by absorbance based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50220841BDBM50220841(BMS-262084 | CHEMBL71037)
Affinity DataIC50: 50nMAssay Description:Inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 303810BDBM303810(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 55nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50542735BDBM50542735(CHEMBL4635286)
Affinity DataIC50: 58nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621693BDBM50621693(CHEMBL5395901)
Affinity DataIC50: 60nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
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