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Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019087
TargetReplicase polyprotein 1ab(2019-nCoV)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM419133(BDBM429386 | GC376)
Affinity DataIC50:  460nMAssay Description:Inhibition of MBP tagged recombinant SARS-CoV-2 main protease using DABCYL-KTSAVLeu(13C6,15N)-Q as substrate incubated for 2 to 3 hrs by mass spectro...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM429505(Remdesivir | US20240034730, Compound Remdesivir | ...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRP using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50615193(CHEMBL5275584)
Affinity DataIC50:  3.22E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRP using ATP substrate preincubated with compound for 30 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM512828(acs.jmedchem.1c00409_ST.423)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of recombinant SARS-CoV-2 main protease expressed in Escherichia coli BL21 using Dabcyl-EDANS and Boc-Abu-Tle-Leu-Gln-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50615194(CHEMBL5268256 | US20240092759, Compound 8)
Affinity DataIC50:  6.38E+3nMAssay Description:Inhibition of recombinant SARS-CoV-2 main protease using Dabcyl-KTSAVLQSGFRKM-E(Edans-NH2) as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50615193(CHEMBL5275584)
Affinity DataIC50:  8.06E+3nMAssay Description:Inhibition of MBP tagged recombinant SARS-CoV-2 main protease using DABCYL-KTSAVLeu(13C6,15N)-Q as substrate incubated for 2 to 3 hrs by mass spectro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed