Report error Found 92 Enz. Inhib. hit(s) with all data for entry = 50022354
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 14nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Agonist activity at STING R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by wash...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 225nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 270nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 290nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair










3D Structure (crystal)





