Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50019448
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619359(CHEMBL5396941)
Affinity DataIC50: 74nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619344(CHEMBL5404112)
Affinity DataEC50:  76nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619359(CHEMBL5396941)
Affinity DataEC50:  83nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619345(CHEMBL5396013)
Affinity DataEC50:  86nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619349(CHEMBL5425701)
Affinity DataEC50:  110nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619344(CHEMBL5404112)
Affinity DataIC50: 110nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619344(CHEMBL5404112)
Affinity DataEC50:  140nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619350(CHEMBL5401622)
Affinity DataEC50:  140nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619348(CHEMBL5410576)
Affinity DataEC50:  150nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619345(CHEMBL5396013)
Affinity DataEC50:  200nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619355(CHEMBL5404283)
Affinity DataEC50:  230nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50182801(CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...)
Affinity DataEC50:  300nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619345(CHEMBL5396013)
Affinity DataIC50: 330nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619354(CHEMBL5408859)
Affinity DataEC50:  370nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50182801(CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...)
Affinity DataIC50: 410nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619346(CHEMBL5395260)
Affinity DataEC50:  470nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619358(CHEMBL5436521)
Affinity DataEC50:  480nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619361(CHEMBL5440207)
Affinity DataEC50:  570nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619354(CHEMBL5408859)
Affinity DataIC50: 650nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619352(CHEMBL5422651)
Affinity DataEC50:  720nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619351(CHEMBL5413426)
Affinity DataEC50:  740nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619341(CHEMBL5440774)
Affinity DataEC50:  970nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619337(CHEMBL5406998)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619346(CHEMBL5395260)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619339(CHEMBL5395546)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619340(CHEMBL5401583)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619342(CHEMBL5414223)
Affinity DataEC50:  1.20E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619337(CHEMBL5406998)
Affinity DataEC50:  1.40E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619361(CHEMBL5440207)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619341(CHEMBL5440774)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619338(CHEMBL5417555)
Affinity DataEC50:  1.90E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619353(CHEMBL5426634)
Affinity DataEC50:  1.90E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619343(CHEMBL5420536)
Affinity DataEC50:  2.20E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619337(CHEMBL5406998)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619347(CHEMBL5410068)
Affinity DataEC50:  3.30E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619338(CHEMBL5417555)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619363(CHEMBL5429998)
Affinity DataEC50:  5.60E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619360(CHEMBL5421765)
Affinity DataEC50:  7.40E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619356(CHEMBL5413060)
Affinity DataEC50: >1.60E+4nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619357(CHEMBL5402801)
Affinity DataEC50: >1.60E+4nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619362(CHEMBL5403195)
Affinity DataEC50: >1.60E+4nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50619344(CHEMBL5404112)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50619345(CHEMBL5396013)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed