Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50021320
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50637221(Fruquintinib | Hmpl-013 | HMPL-013 | HMPL013 | Fru...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRAC-alpha serine/threonine-protein kinase(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50637405(Capivasertib | Azd 5363 | Azd-5363 | AZC5363 | AZD...)
Affinity DataIC50: 3nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50637405(Capivasertib | Azd 5363 | Azd-5363 | AZC5363 | AZD...)
Affinity DataIC50: 7nMAssay Description:Inhibition of AKT3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50637405(Capivasertib | Azd 5363 | Azd-5363 | AZC5363 | AZD...)
Affinity DataIC50: 7nMAssay Description:Inhibition of AKT2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 18nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50637221(Fruquintinib | Hmpl-013 | HMPL-013 | HMPL013 | Fru...)
Affinity DataIC50: 33nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50637221(Fruquintinib | Hmpl-013 | HMPL-013 | HMPL013 | Fru...)
Affinity DataIC50: 35nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEstrogen receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM349630(US10208011, Compound RAD- | US10981887, Compound R...)
Affinity DataIC50: 48nMAssay Description:Inhibition of ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM349630(US10208011, Compound RAD- | US10981887, Compound R...)
Affinity DataIC50: 870nMAssay Description:Inhibition of ERbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed