Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50021165
TargetSerine/threonine-protein kinase mTOR(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50348452(CHEMBL1801204 | US9102670, 1a | AZD-8055)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503137(CHEMBL4516990)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ULK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637636(CHEMBL5568152)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503137(CHEMBL4516990)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM150162(US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50428286(GSK2118436A | DABRAFENIB)
Affinity DataIC50: 5nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase mTOR(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111577(CHEMBL3605055)
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal Sumo-tagged ULK1 (1 to 283 residues) (unknown origin) incubated for 15 to 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637406(CHEMBL4744680)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637637(CHEMBL5565790)
Affinity DataIC50: 14nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271371(CHEMBL4125718)
Affinity DataEC50:  19nMAssay Description:Activation of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 31nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50280093(CHEMBL4170480)
Affinity DataIC50: 45nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637635(CHEMBL5559777)
Affinity DataIC50: 50nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM153737(GSK screening, 34)
Affinity DataIC50: 53nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM379177(US10266549, Example 88 | US10266549, Example 171a ...)
Affinity DataIC50: 108nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085411(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 427nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM379177(US10266549, Example 88 | US10266549, Example 171a ...)
Affinity DataIC50: 711nMAssay Description:Inhibition of ULK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50637403(CHEMBL4542477)
Affinity DataEC50:  800nMAssay Description:Activation of AMPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed