Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50019783
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598905BDBM50598905(CHEMBL5180161)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598923BDBM50598923(CHEMBL5193821)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622966BDBM50622966(CHEMBL5419877)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622971BDBM50622971(CHEMBL5409064)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622965BDBM50622965(CHEMBL5409267)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622967BDBM50622967(CHEMBL5407738)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622968BDBM50622968(CHEMBL5428012)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622974BDBM50622974(CHEMBL5407486)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622964BDBM50622964(CHEMBL5405721)
Affinity DataIC50: 4nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622969BDBM50622969(CHEMBL5398296)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622977BDBM50622977(CHEMBL5432814)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622975BDBM50622975(CHEMBL5421552)
Affinity DataIC50: 6nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622972BDBM50622972(CHEMBL5427450)
Affinity DataIC50: 9nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622958BDBM50622958(CHEMBL5399532)
Affinity DataIC50: 13nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622957BDBM50622957(CHEMBL5439442)
Affinity DataIC50: 30nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622959BDBM50622959(CHEMBL5423878)
Affinity DataIC50: 40nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622973BDBM50622973(CHEMBL5403590)
Affinity DataIC50: 48nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622970BDBM50622970(CHEMBL5439460)
Affinity DataIC50: 57nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622963BDBM50622963(CHEMBL5395154)
Affinity DataIC50: 100nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622956BDBM50622956(CHEMBL5399005)
Affinity DataIC50: 100nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622960BDBM50622960(CHEMBL5404114)
Affinity DataIC50: 158nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622962BDBM50622962(CHEMBL5421173)
Affinity DataIC50: 226nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622961BDBM50622961(CHEMBL5426062)
Affinity DataIC50: 601nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622976BDBM50622976(CHEMBL5393795)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human DHODH in MOLM-13 AML cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622955BDBM50622955(CHEMBL5398316)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of human DHODH by surface plasmon resonance (SPR) based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622955BDBM50622955(CHEMBL5398316)
Affinity DataKd:  1.30E+5nMAssay Description:Inhibition of human DHODH assessed as dissociation constant by surface plasmon resonance (SPR) based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed