Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50021775
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12311BDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of SARS-CoV-2 main protease BetaCoV/Wuhan/WIV04/2019 expressed in Escherichia coli BL21(DE3) cells using FRET as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644757BDBM50644757(CHEMBL5574569)
Affinity DataIC50: 10nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644780BDBM50644780(CHEMBL5563513)
Affinity DataIC50: 10nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644752BDBM50644752(CHEMBL5572085)
Affinity DataIC50: 11nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644778BDBM50644778(CHEMBL5572787)
Affinity DataIC50: 11nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644781BDBM50644781(CHEMBL5565685)
Affinity DataIC50: 11nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496902BDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataIC50: 13nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644781BDBM50644781(CHEMBL5565685)
Affinity DataIC50: 14nMAssay Description:Inhibition of SARS-CoV-1 main protease using DabcylKTSAVLQSGFRKM-(Edan) as substrate preincubated for 30 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644759BDBM50644759(CHEMBL5572795)
Affinity DataIC50: 14nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644751BDBM50644751(CHEMBL5570525)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644782BDBM50644782(CHEMBL5565858)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644749BDBM50644749(CHEMBL5570296)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644775BDBM50644775(CHEMBL5567237)
Affinity DataIC50: 16nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644750BDBM50644750(CHEMBL5571893)
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644756BDBM50644756(CHEMBL5591360)
Affinity DataIC50: 18nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644753BDBM50644753(CHEMBL5562905)
Affinity DataIC50: 20nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 496902BDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataIC50: 20nMAssay Description:Inhibition of SARS-CoV-1 main protease using DabcylKTSAVLQSGFRKM-(Edan) as substrate preincubated for 30 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644755BDBM50644755(CHEMBL5571332)
Affinity DataIC50: 20nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644760BDBM50644760(CHEMBL5574928)
Affinity DataIC50: 20nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644777BDBM50644777(CHEMBL5575793)
Affinity DataIC50: 21nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644765BDBM50644765(CHEMBL5570210)
Affinity DataIC50: 22nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644746BDBM50644746(CHEMBL5573233)
Affinity DataIC50: 23nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644779BDBM50644779(CHEMBL5562781)
Affinity DataIC50: 23nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644774BDBM50644774(CHEMBL5574551)
Affinity DataIC50: 25nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644771BDBM50644771(CHEMBL5567063)
Affinity DataIC50: 25nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644785BDBM50644785(CHEMBL5574420)
Affinity DataIC50: 25nMAssay Description:Inhibition of SARS-CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644745BDBM50644745(CHEMBL5573206)
Affinity DataIC50: 26nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644748BDBM50644748(CHEMBL5595277)
Affinity DataIC50: 26nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644747BDBM50644747(CHEMBL5571608)
Affinity DataIC50: 26nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644763BDBM50644763(CHEMBL5564296)
Affinity DataIC50: 26nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644761BDBM50644761(CHEMBL5573701)
Affinity DataIC50: 27nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644762BDBM50644762(CHEMBL5570816)
Affinity DataIC50: 28nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644773BDBM50644773(CHEMBL5590624)
Affinity DataIC50: 29nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644765BDBM50644765(CHEMBL5570210)
Affinity DataIC50: 30nMAssay Description:Inhibition of SARS-CoV-1 main protease using DabcylKTSAVLQSGFRKM-(Edan) as substrate preincubated for 30 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644770BDBM50644770(CHEMBL5574536)
Affinity DataIC50: 32nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644758BDBM50644758(CHEMBL5562962)
Affinity DataIC50: 37nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644764BDBM50644764(CHEMBL5571280)
Affinity DataIC50: 40nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644754BDBM50644754(CHEMBL5572886)
Affinity DataIC50: 44nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644768BDBM50644768(CHEMBL5575126)
Affinity DataIC50: 45nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644772BDBM50644772(CHEMBL5583904)
Affinity DataIC50: 45nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644769BDBM50644769(CHEMBL5565724)
Affinity DataIC50: 46nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644782BDBM50644782(CHEMBL5565858)
Affinity DataIC50: 48nMAssay Description:Inhibition of SARS-CoV-1 main protease using DabcylKTSAVLQSGFRKM-(Edan) as substrate preincubated for 30 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644748BDBM50644748(CHEMBL5595277)
Affinity DataIC50: 52nMAssay Description:Inhibition of SARS-CoV-1 main protease using DabcylKTSAVLQSGFRKM-(Edan) as substrate preincubated for 30 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644776BDBM50644776(CHEMBL5565166)
Affinity DataIC50: 65nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644767BDBM50644767(CHEMBL5573583)
Affinity DataIC50: 82nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644744BDBM50644744(CHEMBL5593819)
Affinity DataIC50: 100nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644784BDBM50644784(CHEMBL5569851)
Affinity DataIC50: 180nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644766BDBM50644766(CHEMBL5574830)
Affinity DataIC50: 210nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644783BDBM50644783(CHEMBL5594722)
Affinity DataIC50: 400nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644743BDBM50644743(CHEMBL5593300)
Affinity DataIC50: 500nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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