Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50021182
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM129823(US8815926, 102)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human MDM2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50433561(CHEMBL2381408)
Affinity DataKi:  0.880nMAssay Description:Inhibition of human MDM2 by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50237739(CHEMBL4091801)
Affinity DataKi: <1nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50637898(Cgm-097 | Cgm097 | CGM 097 | CGM-097 | CGM097 | NV...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human MDM2 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM454378(US10717742, Example Ia-34 | US10882866, Example Ia...)
Affinity DataIC50: 2nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50637899(CHEMBL5395366)
Affinity DataKi:  2.10nMAssay Description:Inhibition of MDM2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 33nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)