Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50021536
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641817(CHEMBL5570387)
Affinity DataEC50:  2.98E+3nMAssay Description:Agonist activity at STING in wildtype human THP1-Dual cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based luminescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641817(CHEMBL5570387)
Affinity DataEC50:  3.46E+3nMAssay Description:Agonist activity at STING in human THP1-Dual KI-hSTING-R232 cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based lumines...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50582513(CHEMBL5093161)
Affinity DataEC50:  3.66E+3nMAssay Description:Agonist activity at STING in human THP1-Dual KI-hSTING-R232 cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50582513(CHEMBL5093161)
Affinity DataEC50:  4.71E+3nMAssay Description:Agonist activity at STING in wildtype human THP1-Dual cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641818(CHEMBL5573902)
Affinity DataIC50: 7.87E+3nMAssay Description:Displacement of 2'-Fluo-AHC-c-di-GMP from wildtype human STING expressed in Escherichia coli BL21 (DE3) incubated for 5 mins by fluorescence polariza...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50582513(CHEMBL5093161)
Affinity DataIC50: 1.28E+4nMAssay Description:Displacement of 2'-Fluo-AHC-c-di-GMP from wildtype human STING expressed in Escherichia coli BL21 (DE3) incubated for 5 mins by fluorescence polariza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641817(CHEMBL5570387)
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of 2'-Fluo-AHC-c-di-GMP from wildtype human STING expressed in Escherichia coli BL21 (DE3) incubated for 5 mins by fluorescence polariza...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.55E+4nMAssay Description:Agonist activity at STING in wildtype human THP1-Dual cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641818(CHEMBL5573902)
Affinity DataEC50:  1.64E+4nMAssay Description:Agonist activity at STING in human THP1-Dual KI-hSTING-R232 cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based lumines...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataIC50: 1.83E+4nMAssay Description:Displacement of 2'-Fluo-AHC-c-di-GMP from wildtype human STING expressed in Escherichia coli BL21 (DE3) incubated for 5 mins by fluorescence polariza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641816(CHEMBL5569291)
Affinity DataIC50: 1.86E+4nMAssay Description:Displacement of 2'-Fluo-AHC-c-di-GMP from wildtype human STING expressed in Escherichia coli BL21 (DE3) incubated for 5 mins by fluorescence polariza...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.98E+4nMAssay Description:Agonist activity at STING in human THP1-Dual KI-hSTING-R232 cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641816(CHEMBL5569291)
Affinity DataEC50:  2.72E+4nMAssay Description:Agonist activity at STING in wildtype human THP1-Dual cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based luminescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641816(CHEMBL5569291)
Affinity DataEC50:  2.74E+4nMAssay Description:Agonist activity at STING in human THP1-Dual KI-hSTING-R232 cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based lumines...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50641818(CHEMBL5573902)
Affinity DataEC50:  3.70E+4nMAssay Description:Agonist activity at STING in wildtype human THP1-Dual cells assessed as IRF activation incubated for 24 hrs by QUANTI-Luc reagent based luminescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed