Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50021944
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646368(CHEMBL5591775)
Affinity DataKd:  28nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646362(CHEMBL5584171)
Affinity DataKd:  35nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646367(CHEMBL5595428)
Affinity DataKd:  36nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646366(CHEMBL5592841)
Affinity DataKd:  37nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646361(CHEMBL5591922)
Affinity DataKd:  40nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646365(CHEMBL5594440)
Affinity DataKd:  49nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646363(CHEMBL5592699)
Affinity DataKd:  55nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646364(CHEMBL5593675)
Affinity DataKd:  56nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646368(CHEMBL5591775)
Affinity DataKd:  127nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646362(CHEMBL5584171)
Affinity DataKd:  145nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646366(CHEMBL5592841)
Affinity DataKd:  160nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646367(CHEMBL5595428)
Affinity DataKd:  183nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 288nMAssay Description:Inhibition of DNMT1 (unknown origin) using semi-methylated DNA substrate preincubated for 15 mins followed by substrate and [3H-SAM] addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646365(CHEMBL5594440)
Affinity DataKd:  666nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646364(CHEMBL5593675)
Affinity DataKd:  679nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646368(CHEMBL5591775)
Affinity DataIC50: 777nMAssay Description:Inhibition of DNMT1 (unknown origin) using semi-methylated DNA substrate preincubated for 15 mins followed by substrate and [3H-SAM] addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646363(CHEMBL5592699)
Affinity DataKd:  841nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646361(CHEMBL5591922)
Affinity DataKd:  1.16E+3nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646361(CHEMBL5591922)
Affinity DataKd:  4.09E+3nMAssay Description:Binding affinity to human DNMT1 in presence of 10 uM SAM by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646364(CHEMBL5593675)
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of DNMT1 (unknown origin) using semi-methylated DNA substrate preincubated for 15 mins followed by substrate and [3H-SAM] addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646365(CHEMBL5594440)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) using semi-methylated DNA substrate preincubated for 15 mins followed by substrate and [3H-SAM] addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646361(CHEMBL5591922)
Affinity DataIC50: 3.82E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) using semi-methylated DNA substrate preincubated for 15 mins followed by substrate and [3H-SAM] addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646367(CHEMBL5595428)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) using semi-methylated DNA substrate preincubated for 15 mins followed by substrate and [3H-SAM] addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50646362(CHEMBL5584171)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) using semi-methylated DNA substrate preincubated for 15 mins followed by substrate and [3H-SAM] addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50389497(CHEMBL1564869)
Affinity DataKd:  9.46E+4nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50389497(CHEMBL1564869)
Affinity DataKd:  9.46E+4nMAssay Description:Binding affinity to human DNMT1 expressed in Escherichia coli by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed