Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50021826
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50172078(LY-2801653 | Merestinib | US11952364, Example Mere...)
Affinity DataKi:  2nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM28031(N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorop...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50363397(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645266(CHEMBL5594061)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50172078(LY-2801653 | Merestinib | US11952364, Example Mere...)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645266(CHEMBL5594061)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645258(CHEMBL5593609)
Affinity DataIC50: 24nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50146163(CHEMBL3764045)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50146163(CHEMBL3764045)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645258(CHEMBL5593609)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645256(CHEMBL5574745)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM79601(4-[4-[[[4-chloro-3-(trifluoromethyl)anilino]-oxome...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645262(CHEMBL5571331)
Affinity DataIC50: 150nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645263(CHEMBL5568824)
Affinity DataIC50: 170nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645253(CHEMBL5595346)
Affinity DataIC50: 250nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645262(CHEMBL5571331)
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645256(CHEMBL5574745)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645263(CHEMBL5568824)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645260(CHEMBL5565651)
Affinity DataIC50: 380nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645259(CHEMBL5583996)
Affinity DataIC50: 410nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645265(CHEMBL5575208)
Affinity DataIC50: 450nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645257(CHEMBL5574737)
Affinity DataIC50: 520nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645261(CHEMBL5572702)
Affinity DataIC50: 620nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645255(CHEMBL5565430)
Affinity DataIC50: 720nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645253(CHEMBL5595346)
Affinity DataIC50: 750nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645264(CHEMBL5579755)
Affinity DataIC50: 810nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645265(CHEMBL5575208)
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645260(CHEMBL5565651)
Affinity DataIC50: 860nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645259(CHEMBL5583996)
Affinity DataIC50: 920nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645254(CHEMBL5574727)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant c-MET (956 to 1390 residues) expressed in Baculovirus infected Sf9 cell expression system by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645257(CHEMBL5574737)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645255(CHEMBL5565430)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645261(CHEMBL5572702)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645264(CHEMBL5579755)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50645254(CHEMBL5574727)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human recombinant VEGFR2 (805 to 1356 residues) in presence of ATP by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed