Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50022063
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 16nMAssay Description:Inhibition of C-terminal his-tagged human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal his-tagged recombinant human HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50: 40nMAssay Description:Inhibition of C-terminal his-tagged recombinant human HDAC8 using BocLys(TFA)-AM as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 140nMAssay Description:Inhibition of C-terminal flag-tagged recombinant human HDAC2 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM50602194(CHEMBL5188860)
Affinity DataIC50: 600nMAssay Description:Inhibition of C-terminal his-tagged recombinant human HDAC8 using BocLys(TFA)-AM as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50602194(CHEMBL5188860)
Affinity DataIC50: 940nMAssay Description:Inhibition of C-terminal his-tagged human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM50647653(CHEMBL5597296)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of C-terminal his-tagged recombinant human HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50647653(CHEMBL5597296)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of C-terminal his-tagged human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM50647653(CHEMBL5597296)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of C-terminal his-tagged recombinant human HDAC8 using BocLys(TFA)-AM as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM50602194(CHEMBL5188860)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of C-terminal flag-tagged recombinant human HDAC2 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM50602194(CHEMBL5188860)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of C-terminal his-tagged recombinant human HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM50647654(CHEMBL5596998)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of C-terminal his-tagged recombinant human HDAC8 using BocLys(TFA)-AM as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM50647653(CHEMBL5597296)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of C-terminal flag-tagged recombinant human HDAC2 using Boc-Lys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed