Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50021914
LigandPNGBDBM50646100(CHEMBL5591100)
Affinity DataIC50: 5nMAssay Description:Binding affinity to BRD9 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 7.20nMAssay Description:Binding affinity to BRD9 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 129nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) incubated for 1 hr in presence of fluorescein labeled tracer by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataKi:  800nMAssay Description:Binding affinity to GST-tagged wild-type human CRBN incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50628761(CHEMBL5423392)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity to GST-tagged wild-type human CRBN incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to GST-tagged wild-type human CRBN incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50646099(CHEMBL5590084)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to GST-tagged wild-type human CRBN incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) incubated for 1 hr in presence of fluorescein labeled tracer by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to BRD9 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646100(CHEMBL5591100)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) incubated for 1 hr in presence of fluorescein labeled tracer by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed