Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50022090
LigandPNGBDBM50647995(CHEMBL5597392)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin stimulated human PBMC assessed as reduction in IL-1beta release pretreated with LPS for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50647995(CHEMBL5597392)
Affinity DataIC50: 15nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin stimulated mouse BMDMs assessed as reduction in IL-1beta release pretreated with LPS for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataKd:  18nMAssay Description:Binding affinity to human NLRP3 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50647995(CHEMBL5597392)
Affinity DataKd:  18nMAssay Description:Binding affinity to human NLRP3 by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed