Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50022163
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant METTL3/METTL14 (unknown origin) by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50611058(CHEMBL5279050)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant METTL3/METTL14 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of recombinant METTL3/METTL14 (unknown origin) by radioactivity based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of METTL3/METTL14 (unknown origin) using SAM and 5'-GGACUGGACUGGACUGGACU-3' as substrates incubated for 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50621559(CHEMBL5426510)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of METTL3/METTL14 (unknown origin) by MTase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50248106(CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of human recombinant METTL3/METTL14 extracted from baculovirus infected Hi-5 cells using SAM and 5'-ACGAGUCCUGGACUGAAACGGACUUGU-3' as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50030257(CHEBI:67862 | COPTISINE)
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of METTL3/METTL14 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 6.23E+3nMAssay Description:Inhibition of METTL3/METTL14 (unknown origin) using SAM and 5'-GGACUGGACUGGACUGGACU-3' as substrates incubated for 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of METTL3/METTL14 (unknown origin) using SAM and 5'-GGACUGGACUGGACUGGACU-3' as substrates incubated for 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 4.95E+5nMAssay Description:Inhibition of recombinant METTL3/METTL14 (unknown origin) extracted from baculovirus infected Sf9 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed