Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50023033
Affinity DataIC50: 31nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5meC DNA as substrate by FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataKd: 226nMAssay Description:Binding affinity to ALKBH2 (56 to 261 residues)(unknown origin) assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 245nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 276nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 378nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 527nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 851nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 949nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of demethylase activity of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 1meA dsDNA as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human ALKBH3 demethylation by DpnII digestion assayMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of ALKBH3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human ALKBH2 demethylation by DpnII digestion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of FTO (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.96E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of ALKBH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of FTO (unknown origin) using (5'-ATTGTCA(m6 A)CAGCAGA-FAM-3') as substrate incubated for 30 mins by competitive fluorescence polarization...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 6.03E+4nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 7.48E+4nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 7.53E+4nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 8.67E+4nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 9.74E+4nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of demethylase activity of FTO (35 to 505 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 6meA dsDNA as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of demethylase activity of ALKBH5 (66 to 292 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 6meA dsDNA as subs...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of demethylase activity of ALKBH3 (70 to 286 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 1meA dsDNA as subs...More data for this Ligand-Target Pair
