Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50022797
TargetSerine/threonine-protein kinase RIO2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  49nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605906BDBM50605906(CHEMBL5172767)
Affinity DataIC50: 56nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326053BDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  97nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654406BDBM50654406(CHEMBL6145816)
Affinity DataIC50: 98nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634934BDBM50634934(CHEMBL5527885)
Affinity DataKd:  140nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550127BDBM50550127(CHEMBL4781866)
Affinity DataKd:  160nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572241BDBM50572241(DNDI1417016 | CHEMBL2094383)
Affinity DataKd:  200nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550133BDBM50550133(CHEMBL4754518)
Affinity DataKd:  520nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed