Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50023185
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165469BDBM50165469(CHEMBL3797911)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660171BDBM50660171(CHEMBL6133512)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660176BDBM50660176(CHEMBL6168943)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660173BDBM50660173(CHEMBL6152766)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660174BDBM50660174(CHEMBL6164718)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660175BDBM50660175(CHEMBL6161834)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660172BDBM50660172(CHEMBL6161913)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660177BDBM50660177(CHEMBL6141934)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660178BDBM50660178(CHEMBL6144077)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24470BDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660179BDBM50660179(CHEMBL6150642)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 30 mins by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660181BDBM50660181(CHEMBL6165494)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 30 mins by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351632BDBM50351632(CHEMBL498769)
Affinity DataIC50: 6nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660180BDBM50660180(CHEMBL6161945)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 30 mins by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306682BDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 14nMAssay Description:Inhibition of c-MET (unknown origin) by FRET based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302901BDBM50302901(7-methoxy-N-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50: 17nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179801BDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50: 23nMAssay Description:Inhibition of c-MET (unknown origin) by FRET based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179802BDBM179802(3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...)
Affinity DataIC50: 47nMAssay Description:Inhibition of c-MET (unknown origin) by FRET based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660182BDBM50660182(CHEMBL6169161)
Affinity DataIC50: 52nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 30 mins by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222077BDBM222077(6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 53nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 30 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222078BDBM222078(6-Chloro-3-((2-(2,4-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 62nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 30 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625503BDBM50625503(CHEMBL5414728)
Affinity DataIC50: 63nMAssay Description:Inhibition of c-MET (unknown origin) by FRET based Z-Lyte kinase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24467BDBM24467(4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyridazin-3-yl}...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179798BDBM179798(3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...)
Affinity DataIC50: 286nMAssay Description:Inhibition of c-MET (unknown origin) by FRET based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179799BDBM179799(4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...)
Affinity DataIC50: 982nMAssay Description:Inhibition of c-MET (unknown origin) by FRET based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302899BDBM50302899(7-methoxy-N-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306682BDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 5.15E+3nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 30 mins by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302900BDBM50302900(7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222077BDBM222077(6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222077BDBM222077(6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222078BDBM222078(6-Chloro-3-((2-(2,4-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222078BDBM222078(6-Chloro-3-((2-(2,4-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222077BDBM222077(6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Iran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222078BDBM222078(6-Chloro-3-((2-(2,4-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed