Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50023310
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661687BDBM50661687(CHEMBL6147235)
Affinity DataEC50:  5.40nMAssay Description:Inhibition of CDK12 in human MDA-MB-231 cells incubated for 10 hrsMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 13(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661687BDBM50661687(CHEMBL6147235)
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK13 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528813BDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661687BDBM50661687(CHEMBL6147235)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661683BDBM50661683(CHEMBL6150916)
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661682BDBM50661682(CHEMBL6151134)
Affinity DataIC50: 19nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661678BDBM50661678(CHEMBL6144247)
Affinity DataIC50: 32nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661688BDBM50661688(CHEMBL6147094)
Affinity DataIC50: 34nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661680BDBM50661680(CHEMBL6164699)
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661687BDBM50661687(CHEMBL6147235)
Affinity DataEC50:  40nMAssay Description:Inhibition of CDK12 in human MDA-MB-231 cells pretreated with compound for 4 hrs followed by compound washout measured after 3 daysMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661681BDBM50661681(CHEMBL6174210)
Affinity DataIC50: 45nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661677BDBM50661677(CHEMBL6168846)
Affinity DataIC50: 45nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661684BDBM50661684(CHEMBL6147090)
Affinity DataIC50: 51nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661690BDBM50661690(CHEMBL6151865)
Affinity DataIC50: 58nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584000BDBM50584000(CHEMBL4877117)
Affinity DataIC50: 101nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661679BDBM50661679(CHEMBL6151455)
Affinity DataIC50: 108nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661685BDBM50661685(CHEMBL6145029)
Affinity DataIC50: 119nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661689BDBM50661689(CHEMBL6173028)
Affinity DataIC50: 181nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661686BDBM50661686(CHEMBL6142118)
Affinity DataIC50: 223nMAssay Description:Inhibition of CDK12 (unknown origin) using GSRTPMY-NH2 as substrate in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed