Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50029471
LigandChemical structure of BindingDB Monomer ID 50284844BDBM50284844(2-Biphenyl-4-yl-3-methyl-quinoline-4-carboxylic ac...)
Affinity DataKi:  1.70nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284826BDBM50284826(Sodium; 2-biphenyl-4-yl-6-fluoro-3-methyl-quinolin...)
Affinity DataKi:  8nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284843BDBM50284843(2-Biphenyl-4-yl-3-methyl-6-trifluoromethyl-quinoli...)
Affinity DataKi:  8.40nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284834BDBM50284834(2-Biphenyl-4-yl-3,6-dimethyl-quinoline-4-carboxyli...)
Affinity DataKi:  10nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284861BDBM50284861(2-Biphenyl-4-yl-6-fluoro-quinoline-4-carboxylic ac...)
Affinity DataKi:  10nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284867BDBM50284867(Sodium; 6-fluoro-2-(2'-fluoro-4'-hydroxy-biphenyl-...)
Affinity DataKi:  11nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 15339BDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataKi:  12nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284853BDBM50284853(2-Biphenyl-4-yl-6-fluoro-3-methoxy-quinoline-4-car...)
Affinity DataKi:  13nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284858BDBM50284858(2-Biphenyl-4-yl-6-fluoro-3-methylsulfanyl-quinolin...)
Affinity DataKi:  13nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284838BDBM50284838(9-Fluoro-3-phenyl-5,6-dihydro-benzo[c]acridine-7-c...)
Affinity DataKi:  17nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284862BDBM50284862(2-Biphenyl-4-yl-6-chloro-3-methyl-quinoline-4-carb...)
Affinity DataKi:  20nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284830BDBM50284830(Sodium; 6-fluoro-3-methyl-2-(4'-methyl-biphenyl-4-...)
Affinity DataKi:  24nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284846BDBM50284846(2-Biphenyl-4-yl-5-chloro-3-methyl-quinoline-4-carb...)
Affinity DataKi:  25nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284864BDBM50284864(2-(4-Cyclohexyl-phenyl)-6-fluoro-3-methyl-quinolin...)
Affinity DataKi:  28nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284860BDBM50284860(6-Fluoro-3-methyl-2-(4-phenoxy-phenyl)-quinoline-4...)
Affinity DataKi:  29nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284842BDBM50284842(2-Biphenyl-4-yl-3-ethyl-6-fluoro-quinoline-4-carbo...)
Affinity DataKi:  30nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284855BDBM50284855(Sodium; 2-(4'-bromo-biphenyl-4-yl)-6-fluoro-3-meth...)
Affinity DataKi:  38nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284837BDBM50284837(2-(4-tert-Butyl-phenyl)-6-fluoro-3-methyl-quinolin...)
Affinity DataKi:  40nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50201921BDBM50201921(2-Biphenyl-4-yl-6-fluoro-3-hydroxy-quinoline-4-car...)
Affinity DataKi:  40nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284852BDBM50284852(2-(2'-Fluoro-biphenyl-4-yl)-3-methyl-[1,7]naphthyr...)
Affinity DataKi:  48nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284820BDBM50284820(Sodium; 6-fluoro-2-(3'-fluoro-biphenyl-4-yl)-3-met...)
Affinity DataKi:  50nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284859BDBM50284859(Sodium; 6-fluoro-3-methyl-2-(4-thiophen-2-yl-pheny...)
Affinity DataKi:  56nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284854BDBM50284854(6-Fluoro-2-(4-hexyl-phenyl)-3-methyl-quinoline-4-c...)
Affinity DataKi:  60nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284851BDBM50284851(6-Fluoro-3-methyl-2-(3-phenoxy-phenyl)-quinoline-4...)
Affinity DataKi:  63nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284869BDBM50284869(Sodium; 2-(4'-chloro-biphenyl-4-yl)-6-fluoro-3-met...)
Affinity DataKi:  140nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284841BDBM50284841(2-Biphenyl-4-yl-8-chloro-3-methyl-quinoline-4-carb...)
Affinity DataKi:  150nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284828BDBM50284828(Sodium; 6-fluoro-3-methyl-2-(4-pyridin-3-yl-phenyl...)
Affinity DataKi:  200nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284819BDBM50284819(Sodium; 6-fluoro-2-(4'-fluoro-biphenyl-4-yl)-3-met...)
Affinity DataKi:  210nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284866BDBM50284866(2-(2'-Fluoro-biphenyl-4-yl)-3-methyl-[1,8]naphthyr...)
Affinity DataKi:  210nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284833BDBM50284833(6-Biphenyl-4-yl-thieno[2,3-b]pyridine-4-carboxylic...)
Affinity DataKi:  210nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284849BDBM50284849(2-Biphenyl-4-yl-7-chloro-3-methyl-quinoline-4-carb...)
Affinity DataKi:  220nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284824BDBM50284824(Sodium; 6-fluoro-3-methyl-2-(4'-trifluoromethyl-bi...)
Affinity DataKi:  230nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284832BDBM50284832(2-Biphenyl-4-yl-3-methyl-6-methylsulfanyl-quinolin...)
Affinity DataKi:  270nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284825BDBM50284825(6-Fluoro-3-methyl-2-naphthalen-2-yl-quinoline-4-ca...)
Affinity DataKi:  300nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284829BDBM50284829(6-Fluoro-3-methyl-2-(5-phenyl-thiophen-2-yl)-quino...)
Affinity DataKi:  390nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284823BDBM50284823(2-Biphenyl-4-yl-6-fluoro-3-methyl-quinoline-4-carb...)
Affinity DataKi:  400nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284836BDBM50284836(2-(2'-Fluoro-biphenyl-4-yl)-3-methyl-[1,6]naphthyr...)
Affinity DataKi:  420nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284835BDBM50284835(2-Biphenyl-4-yl-6-fluoro-3-methyl-quinolin-4-ol | ...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284865BDBM50284865(6-Fluoro-3-methyl-2-(4-phenyl-butyl)-quinoline-4-c...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284863BDBM50284863(6-Fluoro-3-methyl-2-phenyl-quinoline-4-carboxylic ...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284839BDBM50284839(Sodium; 6-fluoro-2-(4-imidazol-1-yl-phenyl)-3-meth...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284870BDBM50284870(2-Biphenyl-4-yl-6-fluoro-3-methyl-4-tetrazol-1-yl-...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284868BDBM50284868(2-Biphenyl-4-yl-3-methyl-quinoline-4,6-dicarboxyli...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284840BDBM50284840(6-Fluoro-3-methyl-2-naphthalen-1-yl-quinoline-4-ca...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284847BDBM50284847(5-Biphenyl-4-yl-3-methyl-3H-imidazo[4,5-b]pyridine...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284845BDBM50284845(2-Biphenyl-4-yl-6-hydroxy-3-methyl-quinoline-4-car...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284850BDBM50284850(6-Acetylamino-2-biphenyl-4-yl-3-methyl-quinoline-4...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284848BDBM50284848(2-Biphenyl-3-yl-6-fluoro-3-methyl-quinoline-4-carb...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284821BDBM50284821(5-(2'-Fluoro-biphenyl-4-yl)-6-methyl-3H-imidazo[4,...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284822BDBM50284822(2-Biphenyl-4-yl-6-fluoro-3-methyl-quinoline-4-carb...)
Affinity DataKi: >500nMAssay Description:Inhibition measurement of orotate formation from radiolabeled dihydroorotate, using partially purified DHODase isolated from human liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

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