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Found 44 Enz. Inhib. hit(s) with all data for entry = 50029665
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataKi:  0.520nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor beta was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033439(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-phenyl...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor beta was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor beta was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataKi:  0.950nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033439(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-phenyl...)
Affinity DataKi:  1.20nMAssay Description:Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1A receptor in HeLa cells; va...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor beta was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataKi:  2.10nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity towards cloned human 5-hydroxy tryptamine 1A (5-HT1A) receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataKi:  8.90nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataKi:  9.80nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033439(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-phenyl...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards cloned human 5-hydroxy tryptamine 1A (5-HT1A) receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  23nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor beta was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  440nMAssay Description:Binding affinity towards cloned human 5-hydroxy tryptamine 1A (5-HT1A) receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50286672((S)-2-(2-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-a...)
Affinity DataIC50:  60nMAssay Description:Binding affinity towards guinea pig 5-hydroxytryptamine 1D receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was tested for its affinity towards Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was tested for its affinity towards 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was tested for its affinity towards muscarinic (M) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was tested for its affinity towards dopaminergic (D2) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistamine H1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was tested for its affinity towards histaminergic (H 1) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was tested for its affinity towards 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerotonin 2 (5-HT2) receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was tested for its affinity towards Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its affinity towards Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its affinity towards 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its affinity towards muscarinic (M) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its affinity towards dopaminergic (D2) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistamine H1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its affinity towards histaminergic (H 1) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its affinity towards 5-hydroxy tryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerotonin 2 (5-HT2) receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1A receptor in HeLa cells; va...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataEC50:  95nMAssay Description:Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1A receptor in...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataEC50:  30nMAssay Description:Compound was tested for its affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033439(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-phenyl...)
Affinity DataEC50:  50nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039947(2-(5-Nonyloxy-1H-indol-3-yl)-ethylamine | CHEMBL97...)
Affinity DataEC50:  68nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1Dbeta receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataEC50:  0.240nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataEC50:  0.600nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033439(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-phenyl...)
Affinity DataEC50:  0.450nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1Dbeta receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataEC50:  2.80nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataEC50: >1.00E+3nMAssay Description:Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1A receptor in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataEC50:  110nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataEC50:  85nMAssay Description:Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1A receptor in HeLa cells; va...More data for this Ligand-Target Pair
In DepthDetails Article