Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 1257
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10469BDBM10469(CHEMBL424707 | Bis-THA inhibitor 8 | N-[9-(1,2,3,4...)
Affinity DataIC50: 0.770nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10470BDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 3.10nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 8961BDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 44nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10469BDBM10469(CHEMBL424707 | Bis-THA inhibitor 8 | N-[9-(1,2,3,4...)
Affinity DataIC50: 190nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10475BDBM10475(N-(8-phenyloctyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 210nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10474BDBM10474(N-(7-phenylheptyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50: 390nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10470BDBM10470(CHEMBL386423 | Bis-THA inhibitor 9 | N-[10-(1,2,3,...)
Affinity DataIC50: 440nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10472BDBM10472(N-(5-phenylpentyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50: 520nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 8961BDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 590nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10473BDBM10473(N-(6-phenylhexyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 610nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10473BDBM10473(N-(6-phenylhexyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 810nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10474BDBM10474(N-(7-phenylheptyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50: 1.00E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10471BDBM10471(N-(4-phenylbutyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10472BDBM10472(N-(5-phenylpentyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50: 1.50E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10475BDBM10475(N-(8-phenyloctyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 2.40E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10476BDBM10476(N-(9-phenylnonyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 9.30E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10477BDBM10477(N-(10-phenyldecyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50: 9.40E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10476BDBM10476(N-(9-phenylnonyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Mayo Foundation

LigandChemical structure of BindingDB Monomer ID 10477BDBM10477(N-(10-phenyldecyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50: 2.70E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2006
Entry Details Article
PubMed