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Found
119
Enz. Inhib. hit(s) with all data for entry = 5147
Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50008782
(CHEMBL44237 | EPIDEPRIDE | Epidepride;N-(1-Ethyl-p...)
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Affinity Data
Ki: 0.0100nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81492
(BENPERIDOL | CAS_2062-84-2 | NSC_16363)
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Affinity Data
Ki: 0.0270nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50008735
((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
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Affinity Data
Ki: 0.0500nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81492
(BENPERIDOL | CAS_2062-84-2 | NSC_16363)
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Affinity Data
Ki: 0.0660nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85223
(CAS_115368 | NSC_115368 | Perospirone)
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Ki: 0.0900nM
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]pro...)
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Ki: 0.110nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78576
(CIS-THIOTHIXENE | MLS000028463 | SMR000058396 | TH...)
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Ki: 0.120nM
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50034043
(1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperi...)
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Ki: 0.120nM
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130273
(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
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Affinity Data
Ki: 0.130nM
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50095027
((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...)
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Ki: 0.140nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130273
(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
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Affinity Data
Ki: 0.160nM
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
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Affinity Data
Ki: 0.210nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
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Affinity Data
Ki: 0.25nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50017705
(1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetra...)
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Ki: 0.25nM
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
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Ki: 0.300nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
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Affinity Data
Ki: 0.300nM
More data for this Ligand-Target Pair
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85222
(CAS_441351-20-8 | Lurasidone | SM 13496)
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Ki: 0.300nM
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026957
((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
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Ki: 0.300nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 0.350nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81493
(CAS_749-13-3 | TRIFLUORPERIDOL)
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Ki: 0.350nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50034043
(1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperi...)
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Affinity Data
Ki: 0.350nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)
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Ki: 0.400nM
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
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Affinity Data
Ki: 0.450nM
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
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Affinity Data
Ki: 0.540nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50334150
(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
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Affinity Data
Ki: 0.600nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85223
(CAS_115368 | NSC_115368 | Perospirone)
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Affinity Data
Ki: 0.600nM
More data for this Ligand-Target Pair
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
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Affinity Data
Ki: 0.640nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130257
((3E)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dim...)
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Affinity Data
Ki: 0.640nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
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Affinity Data
Ki: 0.660nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85048
(CHEMBL537481 | Glaxo 1192U90)
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Ki: 0.800nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)
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Ki: 0.800nM
More data for this Ligand-Target Pair
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50017705
(1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetra...)
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Affinity Data
Ki: 0.840nM
More data for this Ligand-Target Pair
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
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Affinity Data
Ki: 0.840nM
More data for this Ligand-Target Pair
Target Info
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 0.840nM
More data for this Ligand-Target Pair
Target Info
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
Copy SMILES
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Affinity Data
Ki: 0.960nM
More data for this Ligand-Target Pair
Target Info
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
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Affinity Data
Ki: 1nM
More data for this Ligand-Target Pair
Target Info
PDB
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)
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Affinity Data
Ki: 1.10nM
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)
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Affinity Data
Ki: 1.10nM
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)
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Affinity Data
Ki: 1.20nM
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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ChEBI
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78434
(2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]p...)
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Affinity Data
Ki: 1.20nM
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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Ligand Info
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85222
(CAS_441351-20-8 | Lurasidone | SM 13496)
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Affinity Data
Ki: 1.20nM
More data for this Ligand-Target Pair
Target Info
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
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Affinity Data
Ki: 1.20nM
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85223
(CAS_115368 | NSC_115368 | Perospirone)
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Affinity Data
Ki: 1.30nM
More data for this Ligand-Target Pair
Target Info
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)
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Affinity Data
Ki: 1.5nM
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.5nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Affinity Data
Ki: 1.60nM
More data for this Ligand-Target Pair
Target Info
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Affinity Data
Ki: 1.60nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026957
((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
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Affinity Data
Ki: 1.60nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50010594
(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
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Affinity Data
Ki: 1.80nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
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PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.80nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
Copy BDB DOI
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