Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 8801
TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419194BDBM419194(US10457681, Compound Ia-02 | US10487084, Compound ...)
Affinity DataEC50:  5.90nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419219BDBM419219(US10457681, Compound Ia-04 | US10487084, Compound ...)
Affinity DataEC50:  6.90nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419219BDBM419219(US10457681, Compound Ia-04 | US10487084, Compound ...)
Affinity DataEC50:  7.5nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 420041BDBM420041(US10487084, Compound Ib-02)
Affinity DataEC50:  7.55nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419243BDBM419243(US10457681, Compound Ia-05 | US10487084, Compound ...)
Affinity DataEC50:  8nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419194BDBM419194(US10457681, Compound Ia-02 | US10487084, Compound ...)
Affinity DataEC50:  12.6nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419208BDBM419208(US10457681, Compound Ia-03 | US10487084, Compound ...)
Affinity DataEC50:  15nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419193BDBM419193(US10457681, Compound Ia-01 | US10487084, Compound ...)
Affinity DataEC50:  16nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419258BDBM419258(US10457681, Compound Ia-06 | US10487084, Compound ...)
Affinity DataEC50:  24nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419208BDBM419208(US10457681, Compound Ia-03 | US10487084, Compound ...)
Affinity DataEC50:  26nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419243BDBM419243(US10457681, Compound Ia-05 | US10487084, Compound ...)
Affinity DataEC50:  39.7nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 420041BDBM420041(US10487084, Compound Ib-02)
Affinity DataEC50:  52nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 420040BDBM420040(US10487084, Compound Ib-01)
Affinity DataEC50:  59nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419258BDBM419258(US10457681, Compound Ia-06 | US10487084, Compound ...)
Affinity DataEC50:  88.7nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 420042BDBM420042(US10487084, Compound Ic-01)
Affinity DataEC50:  99nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 420040BDBM420040(US10487084, Compound Ib-01)
Affinity DataEC50:  106nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419193BDBM419193(US10457681, Compound Ia-01 | US10487084, Compound ...)
Affinity DataEC50:  108nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 420042BDBM420042(US10487084, Compound Ic-01)
Affinity DataEC50:  365nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50241029BDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  420nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 419191BDBM419191(US10457681, Compound B | US10508115, Compound B | ...)
Affinity DataEC50:  474nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50440284BDBM50440284(CHEMBL2424780 | US9708325, GS-9620 | US10457681, C...)
Affinity DataEC50:  1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50320067BDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  3.34E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)