Compile Data Set for Download or QSAR
Report error Found 508 Enz. Inhib. hit(s) with all data for entry = 9179
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447547(6-((3-methoxy-4-((6-methylpyridin-3-yl)methoxy)phe...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447636(3-(4-cyclopropylpiperazin-1-yl)-6-((3-methoxy-4-((...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447546(6-((2-fluoro-4-((4-methoxybenzyl)oxy)phenyl)amino)...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447635(6-((3-methoxy-4-((1-propyl-1H-pyrazol-4-yl)methoxy...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447544(6-((3-methoxy-4-(pyrazin-2-ylmethoxy)phenyl)amino)...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447545(6-((6-((4-methoxybenzyl)oxy)pyridin-3-yl)amino)-3-...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447633(6-((3-methoxy-4-((1-ethyl-1H-pyrazol-4-yl)methoxy)...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447632(6-((4-((6-((dimethylamino)methyl)pyridin-3-yl)meth...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447551(6-((4-((3,4-dimethoxybenzyl)oxy)-3-methoxyphenyl)a...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447641(6-((4-((6-cyclopropylpyridin-3-yl)methoxy)-3-metho...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447549(6-((3-fluoro-4-((4-methoxybenzyl)oxy)phenyl)amino)...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447641(6-((4-((6-cyclopropylpyridin-3-yl)methoxy)-3-metho...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447547(6-((3-methoxy-4-((6-methylpyridin-3-yl)methoxy)phe...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447554(6-((3-methoxy-4-((5-methylisoxazol-3-yl)methoxy)ph...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447646(6-((3-methoxy-4-((5-(methoxymethyl)pyridin-2-yl)me...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447555(6-((3-methoxy-4-((4-methoxybenzyl)oxy)phenyl)amino...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447647(6-((3-methoxy-4-(thiophen-3-ylmethoxy)phenyl)amino...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447645(6-((3-methoxy-4-((5-methylthiophen-2-yl)methoxy)ph...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447554(6-((3-methoxy-4-((5-methylisoxazol-3-yl)methoxy)ph...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447646(6-((3-methoxy-4-((5-(methoxymethyl)pyridin-2-yl)me...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447553(6-((3-methoxy-4-((4-methoxybenzyl)oxy)phenyl)(meth...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447645(6-((3-methoxy-4-((5-methylthiophen-2-yl)methoxy)ph...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447551(6-((4-((3,4-dimethoxybenzyl)oxy)-3-methoxyphenyl)a...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447643(6-((4-(furan-2-ylmethoxy)-3-methoxyphenyl)amino)-3...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447552(6-((3-methoxy-4-((6-methoxypyridin-3-yl)methoxy)ph...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447570(3-(4-(2-hydroxyethyl)piperazin-1-yl)-6-((3-methoxy...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447651(6-((4-((6-cyclopropylpyridin-3-yl)methoxy)-3-metho...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447567(6-((4-((4-cyanobenzyl)oxy)-3-methoxyphenyl)amino)-...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447569(6-((4-((3-cyanobenzyl)oxy)-3-methoxyphenyl)amino)-...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447650(6-((3-methoxy-4-((6-methylpyridin-3-yl)methoxy)phe...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447648(6-((3-methoxy-4-(thiophen-2-ylmethoxy)phenyl)amino...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447567(6-((4-((4-cyanobenzyl)oxy)-3-methoxyphenyl)amino)-...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447555(6-((3-methoxy-4-((4-methoxybenzyl)oxy)phenyl)amino...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447647(6-((3-methoxy-4-(thiophen-3-ylmethoxy)phenyl)amino...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447566(6-((3-chloro-4-((4-methoxybenzyl)oxy)phenyl)amino)...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447648(6-((3-methoxy-4-(thiophen-2-ylmethoxy)phenyl)amino...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447654(3-(dimethylamino)-6-((3-methoxy-4-((6-methylpyridi...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447574(3-(1H-imidazol-1-yl)-6-((3-methoxy-4-((6-methoxypy...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447656(6-((4-((1-cyclopropyl-1H-pyrazol-4-yl)methoxy)-3-m...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447572(1-(8-cyano-7-((3-methoxy-4-((4-methoxybenzyl)oxy)p...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447573(6-((3-methoxy-4-((6-methoxypyridin-3-yl)methoxy)ph...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447654(3-(dimethylamino)-6-((3-methoxy-4-((6-methylpyridi...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447571(6-((3-methoxy-4-((6-methylpyridin-3-yl)methoxy)phe...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447572(1-(8-cyano-7-((3-methoxy-4-((4-methoxybenzyl)oxy)p...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447653(6-((3-methoxy-4-((5-methoxypyridin-2-yl)methoxy)ph...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447570(3-(4-(2-hydroxyethyl)piperazin-1-yl)-6-((3-methoxy...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447651(6-((4-((6-cyclopropylpyridin-3-yl)methoxy)-3-metho...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447571(6-((3-methoxy-4-((6-methylpyridin-3-yl)methoxy)phe...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447652(6-((4-((1-(2-fluoroethyl)-1H-pyrazol-4-yl)methoxy)...)
Affinity DataIC50: 27.5nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM447583(6-((3-methoxy-4-((6-(trifluoromethyl)pyridin-3-yl)...)
Affinity DataKi:  27.5nMAssay Description:c-KIT: Inhibition of c-KIT kinase activity by a test compound disclosed herein was estimated by radiometric assay. Standard assay conditions were 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

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